HOPE Logo

HOPE

The Health Outcomes around Pregnancy and Exposure to HIV/ARVs (HOPE) study explored reproductive health choices, including pregnancy, and overall health outcomes, including reproductive health outcomes. HOPE provides the opportunity to inform future advancements for women living with HIV and their families.


Loading…

Protocol Chairs

Photo of Deborah Kacanek

Deborah Kacanek, ScD

Research Scientist

Harvard T.H. Chan School of Public Health

dkacanek@sdac.harvard.edu

Photo of Kathleen Powis

Kathleen M. Powis, MD, MPH, MBA

Assistant Professor in Pediatrics (Harvard Medical School)

Physician, Internal Medicine and Pediatrics (Massachusetts General Hospital)

Research Associate (Division of Immunology and Infectious Diseases at Harvard T.H. Chan School of Public Health)

kpowis@mgh.harvard.edu

Photo of Lynn Yee

Lynn Yee, MD, MPH

Associate Professor, Obstetrics and Gynecology (Maternal Fetal Medicine)

Northwestern Feinberg School of Medicine

lynn.yee@northwestern.edu

DASH Datasets

The Health Outcomes around Pregnancy and Exposure to HIV/ARVs (HOPE) study investigated physical and mental health outcomes and health related behaviors of women living with HIV of reproductive age, including women living with HIV since birth. Health outcomes include HIV disease course, engagement in care, mental health, pregnancy, reproductive health and choices, and cardiometabolic health as well as multi-level social and structural determinants of health and sources of resilience. The framework was informed by a social ecological model, life course perspective, and community engagement. Data collection consists of clinical assessments, online surveys, health interviews, collection of specimens and medical chart abstraction designed to achieve the primary objectives and domain specific aims of the study, as outlined in the protocol. Results from HOPE aim to advance the health of women living with HIV, inform clinical guidelines and shape supportive interventions and policies that address the needs and priorities of women living with HIV and their families.


Source Repository

DASH

Date Released

May 5, 2025